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It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat high blood pressure and chest pain caused by angina. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.</p> <h2>What should I tell my health care providers before I take this medicine?</h2> <p>They need to know if you have any of these conditions:</p> <ul> <li>heart problems, low blood pressure, irregular heartbeat </li> <li>liver disease </li> <li>previous heart attack </li> <li>an unusual or allergic reaction to diltiazem, other medicines, foods, dyes, or preservatives </li> <li>pregnant or trying to get pregnant </li> <li>breast-feeding</li> </ul> <h2>How should I use this medicine?</h2> <p>Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Swallow whole, do not crush or chew. 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Do not take double or extra doses.</p> <h2>What may interact with this medicine?</h2> <p>Do not take this medicine with any of the following:</p> <ul> <li>cisapride </li> <li>hawthorn </li> <li>pimozide </li> <li>ranolazine </li> <li>red yeast rice </li> </ul> <p>This medicine may also interact with the following:</p> <ul> <li>buspirone </li> <li>carbamazepine </li> <li>cimetidine </li> <li>cyclosporine </li> <li>digoxin </li> <li>local anesthetics or general anesthetics </li> <li>lovastatin </li> <li>medicines for anxiety or difficulty sleeping like midazolam and triazolam </li> <li>medicines for high blood pressure or heart problems </li> <li>quinidine </li> <li>rifampin, rifabutin, or rifapentine</li> </ul> <p>This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. 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